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Giulia Caron

University of Torino, Italy

Biography

 

Giulia Caron’s primary scientific activity was lipophilicity, then she moved to the design, experimental determination and computational prediction of physicochemical properties related to ADME properties and to permeability measurements. The integration of Intramolecular Hydrogen Bonding (IMHB) considerations in drug design and the development and application of a tool named Block Relevance (BR) analysis to provide a mechanistic interpretation of QSAR/QSPR models based on the PLS algorithm are two of her main field of interest. To fit new drug discovery exigences she is now focusing on defining a set of experimental and in silico tools for molecular properties evaluation in the bRo5 chemical space

Abstract

Abstract : The Block Relevance (BR) analysis to interpret chromatographic data: application to IAM chromatography in permeability studies